PGC1α Promoter Methylation and Nucleosome Repositioning: Insights Into Exercise and Metabolic Regulation in Skeletal Muscle
نویسندگان
چکیده
منابع مشابه
Acute exercise remodels promoter methylation in human skeletal muscle.
DNA methylation is a covalent biochemical modification controlling chromatin structure and gene expression. Exercise elicits gene expression changes that trigger structural and metabolic adaptations in skeletal muscle. We determined whether DNA methylation plays a role in exercise-induced gene expression. Whole genome methylation was decreased in skeletal muscle biopsies obtained from healthy s...
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ژورنال
عنوان ژورنال: Endocrinology
سال: 2017
ISSN: 0013-7227,1945-7170
DOI: 10.1210/en.2017-00439